Posts by Fred Schwaller

Interviews

The Role of Animal Models in Migraine Research: A Conversation with Andy Russo

In this MSC interview, Professor Russo discusses his path to migraine research, animal models of migraine, and much more.
Triptan responders and non-responders
News

The Response to Triptans: What Counts as Success? What Counts as Failure?

A consensus panel of the European Headache Federation provides definitions of triptan responders and non-responders. The effort could improve migraine treatment and standardize research.
News

A Better Way to Classify Migraine: Linking Symptoms to Patterns of Brain Activity

“Episodic” versus “chronic” migraine is not a biologically meaningful distinction, according to a new fMRI study.
Interviews

A Role for Nutraceuticals in the Treatment of Migraine: A Chat with Paul Durham

In this MSC interview, Dr. Paul Durham discusses his view of migraine as a systemic disorder, a role for nutraceuticals in the treatment of this condition, and much more.
Podcasts

The “Middle Child” of the Opioid Receptor Family: Targeting the Delta Opioid Receptor as a Promising Treatment Approach for Migraine – A Podcast with Amynah Pradhan

Neuroscientist Amynah Pradhan chats about the promise of targeting delta opioid receptors as a way to treat migraine safely and effectively, her recent work on neuronal complexity, and much more.
News

Migraine Changes the Structure of Neurons in the Brain – and Quickly, Too

A new study in mice shows that migraine alters neuronal complexity in pain-processing regions in the brain within hours.
Large clinical trial shows efficacy and safety of e-TNS
News

Large Clinical Trial Shows Efficacy and Safety of External Trigeminal Nerve Stimulation for Migraine Treatment

A study of more than 500 patients across 10 sites in the US reaches its primary outcomes of pain freedom and resolution of most bothersome symptoms. Does this pave the way for more widespread clinical use of neuromodulation?
A Drug That Boosts Naturally Occurring Opioids Eases Migraine Pain in an Animal Model.
News

A Drug That Boosts Naturally Occurring Opioids Eases Migraine Pain in an Animal Model

PL37, which inhibits the enzymes that degrade enkephalins, reduces migraine pain in rats.
Schwann cells and migraine
News

Are Schwann Cells the Bad Guys of Migraine Pain?

New findings in mice show that CGRP activates Schwann cells to sensitize trigeminal neurons, leading to migraine-like pain.
Fred Schwaller

Fred Schwaller is a science writer and communicator based in Berlin, Germany. Fred spent a decade in pain research during his doctoral degree at University College London, UK, and his postdoc at the Max Delbrück Centre in Berlin, Germany. After transferring to science communication in 2020, he has been writing and podcasting about life sciences and medicine, specializing in somatosensation and pain. Follow him on Twitter @SchwallerFred.