Posts by Fred Schwaller
The Role of Animal Models in Migraine Research: A Conversation with Andy Russo
By Fred Schwaller |
In this MSC interview, Professor Russo discusses his path to migraine research, animal models of migraine, and much more.
The Response to Triptans: What Counts as Success? What Counts as Failure?
By Fred Schwaller |
A consensus panel of the European Headache Federation provides definitions of triptan responders and non-responders. The effort could improve migraine treatment and standardize research.
A Better Way to Classify Migraine: Linking Symptoms to Patterns of Brain Activity
By Fred Schwaller |
“Episodic” versus “chronic” migraine is not a biologically meaningful distinction, according to a new fMRI study.
A Role for Nutraceuticals in the Treatment of Migraine: A Chat with Paul Durham
By Fred Schwaller |
In this MSC interview, Dr. Paul Durham discusses his view of migraine as a systemic disorder, a role for nutraceuticals in the treatment of this condition, and much more.
The “Middle Child” of the Opioid Receptor Family: Targeting the Delta Opioid Receptor as a Promising Treatment Approach for Migraine – A Podcast with Amynah Pradhan
By Fred Schwaller |
Neuroscientist Amynah Pradhan chats about the promise of targeting delta opioid receptors as a way to treat migraine safely and effectively, her recent work on neuronal complexity, and much more.
Migraine Changes the Structure of Neurons in the Brain – and Quickly, Too
By Fred Schwaller |
A new study in mice shows that migraine alters neuronal complexity in pain-processing regions in the brain within hours.
Large Clinical Trial Shows Efficacy and Safety of External Trigeminal Nerve Stimulation for Migraine Treatment
By Fred Schwaller |
A study of more than 500 patients across 10 sites in the US reaches its primary outcomes of pain freedom and resolution of most bothersome symptoms. Does this pave the way for more widespread clinical use of neuromodulation?
A Drug That Boosts Naturally Occurring Opioids Eases Migraine Pain in an Animal Model
By Fred Schwaller |
PL37, which inhibits the enzymes that degrade enkephalins, reduces migraine pain in rats.
Are Schwann Cells the Bad Guys of Migraine Pain?
By Fred Schwaller |
New findings in mice show that CGRP activates Schwann cells to sensitize trigeminal neurons, leading to migraine-like pain.
