Posts by Neil Andrews
Migraine Is Not One Disease, but Many: New Insight from a Machine Learning Study
Diagnostic modeling using non-headache features, along with phenotypic modeling, supports the idea of migraine as a spectrum disorder.
Toward a Better Understanding of Vestibular Migraine: A Conversation with María Dolores Villar-Martínez
Dr. Villar-Martínez discusses her interest in vestibular migraine, how her American Headache Society (AHS) Early Career Lecture Award-winning study came about and what the key findings are, her thoughts about the broader vestibular migraine field, and much more.
When the Science and the Clinical Work Come Together: A Conversation with Sinifunanya Nwaobi
Dr. Nwaobi discusses her work on suzetrigine, a sodium channel blocker recently approved for acute pain, as a potential treatment for headache; her research investigating the effects of nitroglycerin on sleep and cerebral blood volume in rodents; her studies of migraine pathophysiology in a rodent model of Ehlers-Danlos syndrome (EDS); and more.
Newly Discovered Sex Differences in the Expression of Thousands of Genes in the Cerebral Cortex
A new study, based on RNA sequencing of single nuclei, could pave the way towards a better understanding of why certain neurological conditions, including migraine, are more common in one sex versus the other.
A New Gene in Hemiplegic Migraine
A recent study links variants in SCN2A, which encodes a sodium channel recognized for its role in epilepsy and autism, to familial and sporadic HM. Electrophysiology experiments and computational neuron models reveal multifaceted effects of the variants on cell excitability.
The Delta Opioid Receptor: New Insight into a Promising Target for Migraine and Pain Treatment
A combination of experimental approaches reveals a comprehensive picture of DOR pharmacology, which could help efforts towards better drug design.
How Chronic Pain Turns into Depression
A new study shows that structural changes in the hippocampus, along with interactions among newborn neurons and microglia in the dentate gyrus, accompany the emergence of affective behaviors over the course of pain. The results have relevance to migraine, too.
February/March 2026 Clinical Research Update: The Latest Findings in Migraine – Part 2
This is Part 2 of MSC’s latest clinical research update.
February/March 2026 Clinical Research Update: The Latest Findings in Migraine – Part 1
Recent research shows successes and challenges for the migraine field.
The Global Burden of Headache: A Consistent but More Detailed Picture – and a Wakeup Call for the Field, Too
Methodological refinements in the Global Burden of Disease Study (GBD) 2023 allow for a more precise estimate of the gender gap in headache, as well as a better understanding of the contribution of medication overuse headache to headache-attributed health loss and how headache burden changes with age. But GBD researchers are also alerting the field to a troubling trend that they don’t want to see continue.
