HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)

By MSC Staff | May 29, 2024 | Posted in

From NIH:

Introduction

This study is part of the Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative® , to speed scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative bolsters research across NIH to (1) improve treatment for opioid misuse and addiction and (2) enhance pain management. More information about the HEAL Initiative is available at: https://heal.nih.gov/.

This notice of funding opportunity (NOFO) aims to promote innovative research to increase knowledge of understudied proteins in the context of pain and pain management. The submission of small research grant (R03) applications is encouraged from institutions and organizations proposing projects leading to a better understanding of eligible proteins listed below.

Small research (R03) grants provide flexibility for initiating discrete, well-defined projects that realistically can be completed in one year and require only limited levels of funding. This program supports different types of projects including, but not limited to, the following:

  • Pilot or feasibility studies;
  • Small, self-contained research projects;
  • Development of research methodology; and/or
  • Development of assays to support compound screening projects;
  • Development of human cell or animal based models.

These awards will support generation of preliminary data and tools around eligible understudied protein(s) with the intent of elucidating the function of these proteins in the context of pain and obtaining sufficient preliminary data and/or research resources for subsequent grant applications and/or drug discovery projects. These grants are non-renewable.

This Funding Opportunity Announcement does not accept applications proposing clinical trial(s).

Read more here.

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