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migraine stigma
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Stigma’s Impact on Chronic Pain – Including Migraine

A new study assesses the contributors to and the effects of pain stigma.
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The Impact of Natural Disasters on Migraine

Recent research shows that victims of the 2018 Japan Floods were more likely to receive newly prescribed migraine treatment, compared to non-victims. A separate study reveals how COVID-19 can affect migraine – sometimes in surprising ways.
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Migraine Changes the Structure of Neurons in the Brain – and Quickly, Too

A new study in mice shows that migraine alters neuronal complexity in pain-processing regions in the brain within hours.
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Pain avoidance in people with migraine
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Pain Avoidance in People with Migraine

New research explores the behaviors and brain regions associated with avoidance of pain, including the role of pain coping.
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AI-ECG
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Modern Technology Applied to a Traditional Approach: A New Way to Assess Atrial Fibrillation Risk in Migraine Patients

A large study of 40,000 people with migraine shows that an artificial intelligence-enabled electrocardiogram predicts an increased risk of atrial fibrillation in patients with migraine with aura.
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Large clinical trial shows efficacy and safety of e-TNS
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Large Clinical Trial Shows Efficacy and Safety of External Trigeminal Nerve Stimulation for Migraine Treatment

A study of more than 500 patients across 10 sites in the US reaches its primary outcomes of pain freedom and resolution of most bothersome symptoms. Does this pave the way for more widespread clinical use of neuromodulation?
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New Links Between Blood Proteins and Migraine
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New Links Between Blood Proteins and Migraine

A genetic study reveals that five of the proteins show a causal relationship with migraine risk.
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A Drug That Boosts Naturally Occurring Opioids Eases Migraine Pain in an Animal Model.
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A Drug That Boosts Naturally Occurring Opioids Eases Migraine Pain in an Animal Model

PL37, which inhibits the enzymes that degrade enkephalins, reduces migraine pain in rats.
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Migraine prevalence
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One in Two People Experience a Headache Disorder, an Updated Review Reports

New research extends upon the Global Burden of Disease study, finding that the prevalence of migraine has increased over time.
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Trigemenial ganglia cell atlas
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Location, Location, Location: Finding the Way to the Cell Types and Genes That Contribute to Migraine

A new trigeminal ganglia cell atlas in mice and people highlights the multiple cell types – both neuronal and non-neuronal – that are involved in migraine. The findings hold promise for the development of new migraine treatments.
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